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Weapons of Mass Destruction

Excerpt from a United States Postal Inspection Service Document

Chemical and biological weapons are sometimes referred to as the "poor man's nuclear weapons" and pose a significant threat in the post-Cold War environment. The relative low cost and simplicity of design and technology make them the weapons of mass destruction choice for a variety of rogue states and terrorist and non-state organizations. Although acts of chemical and biological agent terrorism have not been prevalent in the U.S. up to now, these acts or threats of acts is enough to disrupt operations.

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What should I do if I receive an Anthrax threat by mail?

What is Anthrax?

Anthrax is a bacterial, zoonotic disease caused by Bacillus anthracis, a rod-shaped, gram positive, sporulating organism with the spores constituting the usual infective form. Anthrax occurs in domesticated and wild animals, primarily herbivores, including goats, sheep, cattle, horses, and deer, but other animals may be infected.

The skin form of the human disease may be contracted by handling contaminated hair, wool, hides, flesh, blood or excreta of infected animals and from manufactured products such as bone meal. Infection is introduced through scratches or abrasions of the skin, wounds, inhalation of spores, eating insufficiently cooked infected meat or flies. The spores are very stable and may remain viable for many years in soil and water. They will resist sunlight for varying periods.

What are the symptoms and effects of anthrax?

After an incubation period of 1-7 days, the onset of inhalation anthrax is gradual. Possible symptoms include:

This mild illness can progress rapidly to respiratory distress and shock in 2-4 days followed by a range of more severe symptoms including difficulty breathing, exhaustion, tachycardia, cyanosis and terminal shock can occur. Death usually occurs within 24 hours of respiratory distress onset.

What are the clinical features of anthrax?

Anthrax is an acute bacterial infection of the skin, lungs, or gastrointestinal tract. Infection occurs most commonly via the skin route and only very rarely via the others.

The cutaneous or skin form occurs most frequently on the hands and forearms of persons working with infected livestock or contaminated animal products and represents 95% of cases of human anthrax. It is initially characterized by a papule which progresses to a fluid filled blister with swelling at the site of the infection. The scab that typically forms over the lesion can be black as coal, hence the name anthrax--Greek for coal. With treatment, the case fatality rate should be less than 1% among cutaneous cases. The fatality rate for untreated inhalational or intestinal anthrax is over 90%.

The inhalational form is contracted by inhalation of the spores, occurs mainly among workers handling infected animal hides, wool, and furs. Under natural conditions, inhalational anthrax is exceedingly rare, with only 18 cases having been reported in the United States in the 20th century.

What is the treatment for anthrax?

Treatment with antibiotics beginning one day after exposure to a lethal aerosol challenge with anthrax spores (8,000 - 22,000 spores) has been shown to provide significant protection against death in monkeys, especially when combined with active immunization. Penicillin, doxycycline, and ciproflaxin are all effective against most strains of B anthracis. Penicillin is the drug of choice for naturally ocurring anthrax. If untreated, inhalational anthrax is fatal. For post-exposure prophylaxis the administration of antibiotics should be continued for at least 4 weeks in those exposed and if available, those exposed should receive 3 doses of vaccine before antibiotics are discontinued.

A vaccine is available and consists of a series of 6 doses over 18 months with yearly boosters. The first vaccine of the series must be given at least 6 weeks before exposure to the disease. This vaccine, while known to protect against anthrax acquired through the skin, is also believed to be effective against inhaled spores. While a vaccine does exist for anthrax, its availability to the general public is not widespread.

Effective decontamination can be accomplished by boiling contaminated articles in water for 30 minutes or longer and using some of the common disinfectants. Chlorine is effective in destroying spores and vegetative cells. Remember, anthrax spores are stable, able to resist sunlight for several hours and able to remain alive in soil and water for years.

Additional Resources:

The Federal Bureau of Investigation (FBI) is the lead Federal agency for crisis management for all acts of terrorism and in all threats or incidents of WMD. The FBI will coordinate the Federal Government's efforts to prepare the nation's response community for threats involving weapons of mass destruction (WMD). The National Domestic Preparedness Office (NDPO) works in conjunction with other Federal, State and Local crisis managers specific to WMD and will perform an Interagency Threat Assessment and deploy a Domestic Emergency Support Team (DEST) if a threat is received. To contact them call: 202-324-0259, FBI Special Information Operations Center, SIOC.

The Defense Threat Reduction Agency (DTRA) is a new agency that is charged with reducing the present threat to the U.S. and its allies from WMD and preventing future threats. DTRA focuses Department of Defense efforts to prepare for and respond to chemical or biological attacks. The CB Hotline is 1-800-424-8802. The web site is http://www.dtra.mil/.

The Centers for Disease Control and Prevention (CDC) is responsible for coordinating all public health and would be contacted at the Emergency Preparedness and Response Branch, National Center for Environmental Health to report an incident at 770-488-7100. Their web site is http://cdc.gov.

What constitutes a "suspicious parcel?"

Some typical characteristics Postal Inspectors have detected over the years, which ought to trigger suspicion, include parcels that may:

What should I do if I've received a suspicious parcel in the mail?

 

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